European Journal of Pharmaceutical Sciences 1 September 2023

Title	European Journal of Pharmaceutical Sciences 1 September 2023
Edition	1 September 2023
Call Number
ISBN/ISSN
Author(s)
Subject(s)	bacterial infection Microbial resistance Nanotechnology
Classification
Series Title
GMD	Jurnal
Language	Indonesia
Publisher
Publishing Year	2023
Publishing Place
Collation
Abstract/Notes	ABSTRACT Microbial resistance has increased in recent decades as a result of the extensive and indiscriminate use of an- tibiotics. The World Health Organization listed antimicrobial resistance as one of ten major global public health threats in 2021. In particular, six major bacterial pathogens, including third-generation cephalosporin-resistant Escherichia coli, methicillin-resistant Staphylococcus aureus, carbapenem-resistant Acinetobacter baumannii, Kleb- siella pneumoniae, Streptococcus pneumoniae, and Pseudomonas aeruginosa, were found to have the highest resistance-related death rates in 2019. To respond to this urgent call, the creation of new pharmaceutical technologies based on nanoscience and drug delivery systems appears to be the promising strategy against mi- crobial resistance in light of recent advancements, particularly the new knowledge of medicinal biology. Nanomaterials are often defined as substances having sizes between 1 and 100 nm. If the material is used on a small scale; its properties significantly change. They come in a variety of sizes and forms to help provide dis- tinguishing characteristics for a wide range of functions. The field of health sciences has demonstrated a strong interest in numerous nanotechnology applications. Therefore, in this review, prospective nanotechnology-based therapeutics for the management of bacterial infections with multiple medication resistance are critically examined. Recent developments in these innovative treatment techniques are described, with an emphasis on preclinical, clinical, and combinatorial approaches.
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