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<title>Asian Journal of Pharmaceutical Sciences Volume 20, Issue 6 2025</title>
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<place><placeTerm type="text">China</placeTerm></place>
<publisher>China Medical University</publisher>
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<issuance>monographic</issuance>
<edition>Volume 20, Issue 6 2025</edition>
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<languageTerm type="text">Indonesia</languageTerm>
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<note>a b s t r a c t
Wound healing is a series of complex biological events that are tightly coordinated
by the body. However, this physiological process is compromised in a pathological
setting and underlie conditions including diabetic complications, infectious diseases
and chronic inflammatory conditions. Clinically, this translates to multiple pathological
features collectively exhibited (microbial colonization, chronic inflammation and impaired
regenerative processes). Due to these pathological features, modern wound care approaches
have changed from simple passive coverage products to advanced dressing systems which
incorporate multifunctional therapies. To comprehensively elucidate recent advancements
in advanced wound dressings for drug delivery applications, this review systematically
examines material-driven drug release strategies through multiple analytical dimensions.
The discussion encompasses structurally engineered controlled-release systems featuring
bilayer architectures, layer-by-layer assembly techniques and porous matrix designs, as
well as intelligent stimulus-responsive mechanisms based on physicochemical properties,
including physical condition modulation, swelling/degradation behavior control, dynamic
chemical bond engineering and crosslinking network optimization. Through critical
analysis of these cutting-edge technologies, this article provides insightful perspectives on their clinical translation potential and future trajectories.</note>
<subject authority=""><topic>Wound healing</topic></subject>
<subject authority=""><topic>drug delivery</topic></subject>
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