Asian Journal of Pharmaceutical Sciences Volume 20, Issue 3 2025

Title	Asian Journal of Pharmaceutical Sciences Volume 20, Issue 3 2025
Edition	Volume 20, Issue 3 2025
Call Number
ISBN/ISSN
Author(s)
Subject(s)	drug delivery Microneedle Target
Classification
Series Title
GMD	Jurnal
Language	Indonesia
Publisher	China Medical University
Publishing Year	2025
Publishing Place	China
Collation
Abstract/Notes	a b s t r a c t Microneedle-mediated drug delivery systems (MDDS) have experienced robust growth in recent years, with designers leveraging their creativity to apply these systems for direct drug delivery to the skin, mucous membranes, blood vessel walls and even internal organs. In order to achieve precise drug delivery, various delicately conceived drug release modes based on MDDS have been developed. Herein, to elucidate the design concepts of numerous reported MDDS, we have categorized them into two levels (Level-I MDDS and Level-II MDDS) depending on whether nanoscale and microscale carriers are integrated within the microneedles. In this work, the design strategies of MDDS, as well as the current status of their applications in targeted and intelligent drug delivery were reviewed, while their prospects and challenges for future industrialization and clinical applications were also discussed.
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