mixed material bibliography China China Medical University 2025 monographic Volume 20, Issue 3 2025 id Indonesia

Jurnal

a b s t r a c t Microneedle-mediated drug delivery systems (MDDS) have experienced robust growth in recent years, with designers leveraging their creativity to apply these systems for direct drug delivery to the skin, mucous membranes, blood vessel walls and even internal organs. In order to achieve precise drug delivery, various delicately conceived drug release modes based on MDDS have been developed. Herein, to elucidate the design concepts of numerous reported MDDS, we have categorized them into two levels (Level-I MDDS and Level-II MDDS) depending on whether nanoscale and microscale carriers are integrated within the microneedles. In this work, the design strategies of MDDS, as well as the current status of their applications in targeted and intelligent drug delivery were reviewed, while their prospects and challenges for future industrialization and clinical applications were also discussed. Target Microneedle drug delivery PERPUSTAKAAN SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA REPOSITORY JIN0126 Perpus.Akfarsam (Jurnal Farmasi Internasional) 615 ASI Volume 20, Issue 3 2025 Volume_20%2C_Issue_3.jpeg.jpeg 2343 2026-07-10 12:28:14 2026-07-10 12:30:47 machine generated