mixed material bibliography China China Medical University 2025 monographic Volume 20, Issue 1 2025 id Indonesia

Jurnal

a b s t r a c t The recent commercialization of gene products has sparked significant interest in gene therapy, necessitating efficient and precise gene delivery via various vectors. Currently, viral vectors and lipid-based nanocarriers are the predominant choices and have been extensively investigated and reviewed. Beyond these vectors, polymeric nanocarriers also hold the promise in therapeutic gene delivery owing to their versatile functionalities, such as improving the stability, cellar uptake and endosomal escape of nucleic acid drugs, along with precise delivery to targeted tissues. This review presents a brief overview of the status quo of the emerging polymeric nanocarriers for therapeutic gene delivery, focusing on key cationic polymers, nanocarrier types, and preparation methods. It also highlights targeted diseases, strategies to improve delivery efficiency, and potential future directions in this research area. The review is hoped to inspire the development, optimization, and clinical translation of highly efficient polymeric nanocarriers for therapeutic gene delivery. Cationic polymers Polymeric nanocarriers PERPUSTAKAAN SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA REPOSITORY JIN0124 Perpus.Akfarsam (Jurnal Farmasi Internasional) 615 ASI Volume 20, Issue 1 2025 Volume_20%2C_Issue_1.jpeg.jpeg 2341 2026-07-10 10:17:58 2026-07-10 12:21:32 machine generated