mixed material bibliography China China Medical University 2024 monographic Volume 19, Issue 5 2024 id Indonesia

Jurnal

a b s t r a c t Metal-organic frameworks (MOFs) offer innovative solutions to the limitations of traditional oral drug delivery systems through their unique combination of metal ions and organic ligands. This review systematically examines the structural properties and principles of MOFs, setting the stage for their application in drug delivery. It discusses various classes of MOFs, including those based on zirconium, iron, zinc, copper, titanium, aluminum, potassium, and magnesium, assessing their drug-loading capacities, biocompatibility, and controlled release mechanisms. The effectiveness of MOFs is illustrated through case studies that highlight their capabilities in enhancing drug solubility, providing protection against the harsh gastrointestinal environment, and enabling precise drug release. The review addresses potential challenges, particularly the toxicity concerns associated with MOFs, and calls for further research into their biocompatibility and interactions with biological systems. It concludes by emphasizing the potential of MOFs in revolutionizing oral drug delivery, highlighting the critical need for comprehensive research to harness their full potential in clinical applications. drug delivery Bioavailability Metal-organic frameworks PERPUSTAKAAN SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA REPOSITORY JIN0122 Perpus.Akfarsam (Jurnal Farmasi Internasional) 615 ASI Volume 19, Issue 5 2024 Volume_19%2C_Issue_5.jpeg.jpeg 2339 2026-07-10 09:42:09 2026-07-10 09:44:35 machine generated