Asian Journal of Pharmaceutical Sciences Volume 19, Issue 3 2024

Title	Asian Journal of Pharmaceutical Sciences Volume 19, Issue 3 2024
Edition	Volume 19, Issue 3 2024
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ISBN/ISSN
Author(s)
Subject(s)	Injectable Sprayable Precision therapy
Classification
Series Title
GMD	Jurnal
Language	Indonesia
Publisher	China Medical University
Publishing Year	2024
Publishing Place	China
Collation
Abstract/Notes	a b s t r a c t Precision therapy has become the preferred choice attributed to the optimal drug concentration in target sites, increased therapeutic efficacy, and reduced adverse effects. Over the past few years, sprayable or injectable thermosensitive hydrogels have exhibited high therapeutic potential. These can be applied as cell-growing scaffolds or drug-releasing reservoirs by simply mixing in a free-flowing sol phase at room temperature. Inspired by their unique properties, thermosensitive hydrogels have been widely applied as drug delivery and treatment platforms for precision medicine. In this review, the state-of-the- art developments in thermosensitive hydrogels for precision therapy are investigated, which covers from the thermo-gelling mechanisms and main components to biomedical applications, including wound healing, anti-tumor activity, osteogenesis, and periodontal, sinonasal and ophthalmic diseases. The most promising applications and trends of thermosensitive hydrogels for precision therapy are also discussed in light of their unique features.
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