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<title>Asian Journal of Pharmaceutical Sciences Volume 19, Issue 1 2024</title>
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<place><placeTerm type="text">China</placeTerm></place>
<publisher>China Medical University</publisher>
<dateIssued>2024</dateIssued>
<issuance>monographic</issuance>
<edition>Volume 19, Issue 1 2024</edition>
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<languageTerm type="text">Indonesia</languageTerm>
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<note>a b s t r a c t
Hydrogen sulfide (H2S) is a toxic, essential gas used in various biological and physical
processes and has been the subject of many targeted studies on its role as a new gas
transmitter. These studies have mainly focused on the production and pharmacological
side effects caused by H2S. Therefore, effective strategies to remove H2S has become a
key research topic. Furthermore, the development of novel nanoplatforms has provided
new tools for the targeted removal of H2S. This paper was performed to review the
association between H2S and disease, related H2S inhibitory drugs, as well as H2S responsive
nanoplatforms (HRNs). This review first analyzed the role of H2S in multiple tissues and
conditions. Second, common drugs used to eliminate H2S, as well as their potential for
combination with anticancer agents, were summarized. Not only the existing studies on
HRNs, but also the inhibition H2S combined with different therapeutic methods were
both sorted out in this review. Furthermore, this review provided in-depth analysis of
the potential of HRNs about treatment or detection in detail. Finally, potential challenges
of HRNs were proposed. This study demonstrates the excellent potential of HRNs for
biomedical applications.</note>
<subject authority=""><topic>Hydrogen sulfide</topic></subject>
<subject authority=""><topic>challenges</topic></subject>
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