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<title>Media Farmasi Jurnal Ilmu Farmasi Vol 22 No 1 2025</title>
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<publisher>Universitas Gadjah Mada</publisher>
<dateIssued>2025</dateIssued>
<issuance>monographic</issuance>
<edition>Vol 22 No 1 2025</edition>
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<languageTerm type="text">Indonesia</languageTerm>
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<note>The fermented product sector can produce kefir for use in cosmetic 
preparations. Kefir has weak storage stability and strong antioxidant 
properties, making it a suitable raw material for cosmetic formulations. 
The purpose of this study is to determine the best concentration of peanut 
kefir in Peel-off mask Arachi through antioxidant activity and physical 
stability during seven cycles of room temperature storage and freeze-thaw 
(4&plusmn;2&ordm;C and 40&plusmn;2&ordm;C). Using the DPPH method based on the IC50 value, 
the antioxidant activity test was conducted. It was retested after 7 cycles 
or 28 days. At ambient temperature and freeze-thaw temperature, 
organoleptic tests, pH, adhesion, and spreadability were conducted in 
cycles ranging from 0 to 7. The peel-off kefir mask preparations with F1 
(0.5%), F2 (1%), and F3 (2%), concentrations created a homogeneous, 
viscous preparation that was stable at room temperature and freeze-thaw 
stable for seven cycles, according to the results. In terms of the pH test, 
the sample showed a drop in pH following storage, stable adhesion for up 
to seven cycles. However, for F1, the adhesion was not stable in either 
scenario. With a significant activity category, the formula's antioxidant 
activity also declines in IC50 values. Therefore, it can be said that even 
though the peel-off mask preparation changed after storage in a few 
different ways, it still falls short of the threshold in terms of the physical 
characteristics of the cosmetic preparation.</note>
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