Journal Of Tropical Pharmacy and Cemistry Vol 9 No 1 (2025)

Title	Journal Of Tropical Pharmacy and Cemistry Vol 9 No 1 (2025)
Edition	Vol 9 No 1 (2025)
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ISBN/ISSN
Author(s)
Subject(s)	diet Gut Microbiome nutrition preventive medicine
Classification
Series Title
GMD	Jurnal
Language	Indonesia
Publisher	Universitas Mulawarman
Publishing Year	2025
Publishing Place	Samarinda
Collation
Abstract/Notes	Abstract The gut microbiome is a complex and dynamic ecosystem that plays a crucial role in human health, influencing various physiological processes including nutrition, metabolism, immune function, and mental well-being. This review explores the intricate relationship between the gut microbiome and nutrition, highlighting its impact on overall health. The composition and diversity of the gut microbiota are shaped by factors such as diet, age, genetics, and environmental conditions. Dietary patterns, particularly the consumption of probiotics, fermented foods, and specific macronutrients, can modulate the gut microbiome, affecting nutrient metabolism, vitamin synthesis, and the production of beneficial compounds like short-chain fatty acids. These microbial metabolites influence host health through mechanisms such as immune regulation and metabolic processes. The gut microbiome also plays a pivotal role in the gut-brain axis, a bidirectional communication network that influences mental health and cognitive function. Dysbiosis, an imbalance in the gut microbiota, has been linked to numerous health conditions, including obesity, metabolic disorders, and autoimmune diseases. While dietary interventions show promise in restoring microbial balance and improving health outcomes, challenges remain in gut microbiome research, including technical and methodological limitations, the need for standardization, and the complexity of human-microbiome interactions. As our understanding of the gut microbiome continues to evolve, it holds significant potential for advancing preventive medicine and improving overall human health. Future research should focus on overcoming current challenges to develop more personalized and effective microbiome-based therapies. Keywords: Gut Microbiome, nutrition, diet, preventive medicine, microbiome-based therapies.
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