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<title>Marmara Pharmaceutical Journal of Research in Pharmacy Journal of Research in Pharmacy 2023 , Vol 27 , Issue 1</title>
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<publisher>marmara University</publisher>
<dateIssued>2023</dateIssued>
<issuance>monographic</issuance>
<edition>2023 , Vol 27 , Issue 1</edition>
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<languageTerm type="text">Indonesia</languageTerm>
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<note>ABSTRACT: The main aim of this review is to investigate published research that related nanoemulsions
formulations as the for improving of acne and to evaluate the recent developments and future of nanoemulsions for
acne care. Nanoemulsion, skin penetration, acne vulgaris, topical drug delivery using as keywords were sequentially
searched three databases (PubMed, ScienceDirect, Google Scholar). Following the removal of duplications and
irrelevant results, research articles and reviews were included in the final literature overview. Systemic therapy
includes anti-inflammatory and antibiotics drugs that can bring on undesirable adverse. On the other hand, the low
solubility in water of the drug and insufficient penetration through the skin limits the drugs&rsquo; topical administration.
Innovative topical nanoemulsion systems can be very impactful to decrease the side effects of drugs and provide
tremendous drug penetration through the skin. They provide advantage over traditional topical medications by
enhancing bioavailability of drugs, and the persistency of drugs in the skin layers. Furthermore, nanoemulsions have
significant potential to overcome the drawbacks of the conventional dosage forms contains natural molecules and
essential oils for acne therapy. Additionally, some comparative studies showed that nanoemulsions increase the
permeability of the drug molecule through the skin more than other nanocarriers (SLN, NLC).

KEYWORDS: Acne vulgaris; drug delivery; nanocarriers; nanoemulsion; skin penetration; topical</note>
<subject authority=""><topic>topical</topic></subject>
<subject authority=""><topic>skin penetration</topic></subject>
<subject authority=""><topic>nanoemulsion</topic></subject>
<subject authority=""><topic>nanocarriers</topic></subject>
<subject authority=""><topic>drug delivery</topic></subject>
<subject authority=""><topic>Acne vulgaris</topic></subject>
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<physicalLocation>PERPUSTAKAAN SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA REPOSITORY</physicalLocation>
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