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<title>Indonesia Journal of Pharmacy Vol 35 No 2 2024</title>
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<publisher>Universitas Gadjah Mada</publisher>
<dateIssued>2024</dateIssued>
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<edition>Vol 35 No 2 2024</edition>
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<languageTerm type="text">Indonesia</languageTerm>
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<note>Wound healing treatment is a challenging strategy in skin drug
delivery due to its complexities. During wound healing stages, fibroblasts
deposit extracellular matrix components, which majority is collagen. Issues
related to collagen production, including scar formation, and delayed wound
healing are essential in wound healing research. Hence, recent studies have
focused on assessing macroscopic and microscopic collagen fibers
qualitatively and quantitatively. Macroscopic analysis of collagen includes
two-dimensional (2D) photographs, planimetric assessments, ultrasonic
imaging, and 3D scanning of wounds; as well as histology-based
microscopically scoring. Thus, the quantitative assessment of collagen
involves Scar Index quantification and collagen content measurement using
ImageJ. To date, a comprehensive analysis combining those methods could
provide insight for pharmacists, dermatologists, and skin researchers to
conduct a precise assessment of the wound healing process.

Keywords: skin, scar, extracellular matrix, dermatologist</note>
<subject authority=""><topic>dermatologist</topic></subject>
<subject authority=""><topic>extracellular matrix</topic></subject>
<subject authority=""><topic>scar</topic></subject>
<subject authority=""><topic>skin</topic></subject>
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