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<title>Media Farmasi Jurnal Ilmu Farmasi Vol 20 No 1 2023</title>
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<place><placeTerm type="text">Jogjakarta</placeTerm></place>
<publisher>Universitas Ahmad Dahlan</publisher>
<dateIssued>2023</dateIssued>
<issuance>monographic</issuance>
<edition>Vol 20 No 1 2023</edition>
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<languageTerm type="text">Indonesia</languageTerm>
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<note>The entry and proliferation of microorganisms, such as bacteria, cause
skin infections. One of the bacteria that causes skin infections is
Staphylococcus epidermidis. Sappan (Caesalpinia sappan L.) wood has
been known to have various pharmacology activities, one of which is
antibacterial, so its activities need to be developed and improved. This
study aimed to determine the activity of the methanol extract of Sappan
(C. sappan L.) wood as an antibacterial against S. epidermidis. This
research was conducted by extracting Sappan wood powder with 96%
methanol as solvent using the Ultrasound-Assisted Extraction (UAE)
method and testing for antibacterial activity with concentrations of 25%,
50%, 75% and 100% using the disc method. Results showed that the
methanol extract of Sappan wood had an antibacterial activity; the highest
inhibition zone at a concentration of 75% was 29.25 mm. Sappan wood
was expected to be a promising alternative therapy for overcoming acne
problems and can increase economic value for the wider community.</note>
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