Tropical Journal of Natural Product Research Vol. 5(7) pp 1166-1322 July 2021

Title	Tropical Journal of Natural Product Research Vol. 5(7) pp 1166-1322 July 2021
Edition	Vol. 5(7) pp 1166-1322 July 2021
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GMD	Karya Tulis Ilmiah
Language	Indonesia
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Abstract/Notes	Snakebite envenomation associated toxicity and death is an important and widely underestimated health issue in the African, Asian and some American provinces. It usually has great impact on larger population especially from remote, poorly developed tropical communities with the lowest quality of life indices. The only treatment available for this Neglected Tropical Disease (NTD) is the anti-snake venom (ASV) that has limitations for its usage due to its availability, affordability and associated adverse events. Hence, enhancement of current therapeutic regime and addition of multiple treatment options for snakebite management is inevitable to reduce the mortality and morbidity. The folk and traditional medicines especially plants, as herbal antidotes against snake bite have been in use for centuries with notable success. However, a comprehensive and ethnopharmacological approach is essential to study the various plants and their bioactive components needed to treat snakebite. The review aims to provide compiled information about snake envenomation, biomolecules involved in mechanism of toxicity along with various plants and their constituents useful against snake bite. Related literature available on the various search engines as Google, Google Scholar, PubMed, Medline database, Science Direct, Research Gate were explored and thoroughly read for compilation of information. The review endeavored to provide in-depth knowledge about snake envenomation and its treatment strategies with focus on medicinal plants and its bioactive compounds useful to mitigate venom and future perceptions. It will surely help researchers in the field for development of better treatment options for snakebite envenomation and associated complications. Keywords: Snakes, Antivenom, Traditional medicine, Snake envenomation.
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