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Title Journal Of Tropical Pharmacy and Cemistry Vol 4 no 4 Juli-Desember 2020
Edition Vol 4 no 4 Juli-Desember 2020
Call Number
ISBN/ISSN
Author(s) Fakultas Farmasi Unmul - Personal Name
Subject(s) farmasi
Classification
Series Title
GMD Karya Tulis Ilmiah
Language Indonesia
Publisher Universitas Mulawarman
Publishing Year 2020
Publishing Place Samarinda
Collation
Abstract/Notes Abstract
Antirrhinum Orontium is belonging to the family Plantaginacea commonly known as lesser snapdragon
which is a flowering plant belongs to genus Antirrhinum. It was traditionally used in treatment of Tumor,
Eye inflammation and Ulcer. Antirrhinum Orontium contains mostly tertiary alkaloids bases one of them
is identified as 4-methyl-2, 6-naphthyridine and Choline is identified as quaternary base. The recent study
is to investigate the antibacterial activity of Ethyl acetate, Dichloromethane, Hexane and Water extracts
of Antirrhinum Orontium, against the pathogen like Escherichia coli and Staphylococcus aureus. Both the
Soxhlet and Maceration water extract were found more active from the other extract against Escherichia
coli and Staphylococcus aureus by using agar well diffusion method. The measured zone of inhibition for
Soxhlet water extract is 21±0.05mm and Maceration water extract is 20±0.05mm against gram positive
Staphylococcus aureus, while for gram negative Escherichia coli 23±0.05mm is measured for Soxlet and
21±0.05mm measured for Maceration water extracts.
Keywords: Antirrhinum Orontium, Antibacterial, Plantaginaceae, Escherichia coli, Staphylococcus

aureus
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