Indonesia Journal of Pharmacy Vol 27 no 1 Januari-Maret 2016

Title	Indonesia Journal of Pharmacy Vol 27 no 1 Januari-Maret 2016
Edition	Indonesia J.Pharm
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ISBN/ISSN
Author(s)	Faculty of Farmacy UGM - Personal Name
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Series Title
GMD	Karya Tulis Ilmiah
Language	Indonesia
Publisher	Universitas Gadjah Mada
Publishing Year	2016
Publishing Place	Jogjakarta
Collation
Abstract/Notes	ABSTRACT Traditional pipelines feeding drugs coming to the market are declining. This is one of the reasons why nowadays the previous ly abandoned natural extract drug discovery programs are slowly coming back. In this scenario, small molecular metabolites from plants and single cell marine or soil organisms are gaining interest in pharmaceutical research again. Animal venoms are another source for finding new biopharmaceutical lead molecules and research interest in discovering bioactive molecules from venoms is rising. Venoms comprise often highly selective and potent bioactive peptides and small proteins for receptors and enzymes that are valid drug targets. This work discusses drug discovery research on bioactive compounds in venoms and gives older and more recent examples of bioactive compounds found in venoms from different animals. Common pharmaceutical targets that different classes of venom toxins interact with and information on developmental stages of several medicinal venom peptides are also discussed. Key words:venom,toxin, drugdiscovery, peptide,pharmaceutical activity
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