Faculty of Farmacy UGM Primary Author mixed material bibliography Jogjakarta Universitas Gadjah Mada 2016 monographic Indonesia J.Pharm id Indonesia

Karya Tulis Ilmiah

ABSTRACT Traditional pipelines feeding drugs coming to the market are declining. This is one of the reasons why nowadays the previous ly abandoned natural extract drug discovery programs are slowly coming back. In this scenario, small molecular metabolites from plants and single cell marine or soil organisms are gaining interest in pharmaceutical research again. Animal venoms are another source for finding new biopharmaceutical lead molecules and research interest in discovering bioactive molecules from venoms is rising. Venoms comprise often highly selective and potent bioactive peptides and small proteins for receptors and enzymes that are valid drug targets. This work discusses drug discovery research on bioactive compounds in venoms and gives older and more recent examples of bioactive compounds found in venoms from different animals. Common pharmaceutical targets that different classes of venom toxins interact with and information on developmental stages of several medicinal venom peptides are also discussed. Key words:venom,toxin, drugdiscovery, peptide,pharmaceutical activity PERPUSTAKAAN SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA REPOSITORY JN0113 Perpus.Akfarsam (Jurnal Nasional) 051 PAC i vol 27 no 1 2016 1484 2022-03-17 07:25:44 2022-03-25 09:40:17 machine generated