Indonesia Journal of Pharmacy Vol 35 No 2 2024

Title	Indonesia Journal of Pharmacy Vol 35 No 2 2024
Edition	Vol 35 No 2 2024
Call Number
ISBN/ISSN
Author(s)
Subject(s)	skin scar extracellular matrix dermatologist
Classification
Series Title
GMD	Karya Tulis Ilmiah
Language	Indonesia
Publisher	Universitas Gadjah Mada
Publishing Year	2024
Publishing Place	Jogjakarta
Collation
Abstract/Notes	Wound healing treatment is a challenging strategy in skin drug delivery due to its complexities. During wound healing stages, fibroblasts deposit extracellular matrix components, which majority is collagen. Issues related to collagen production, including scar formation, and delayed wound healing are essential in wound healing research. Hence, recent studies have focused on assessing macroscopic and microscopic collagen fibers qualitatively and quantitatively. Macroscopic analysis of collagen includes two-dimensional (2D) photographs, planimetric assessments, ultrasonic imaging, and 3D scanning of wounds; as well as histology-based microscopically scoring. Thus, the quantitative assessment of collagen involves Scar Index quantification and collagen content measurement using ImageJ. To date, a comprehensive analysis combining those methods could provide insight for pharmacists, dermatologists, and skin researchers to conduct a precise assessment of the wound healing process. Keywords: skin, scar, extracellular matrix, dermatologist
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