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Title Journal Of Tropical Pharmacy and Cemistry Vol. 5 No. 4 Juli-Desember (2021)
Edition Vol. 5 No. 4 Juli-Desember (2021)
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ISBN/ISSN
Author(s) Fakultas Farmasi Unmul - Personal Name
Subject(s) farmasi
Classification
Series Title
GMD Karya Tulis Ilmiah
Language Indonesia
Publisher Universitas Mulawarman
Publishing Year 2021
Publishing Place Samarinda
Collation
Abstract/Notes Abstract
Developing countries use medicinal plants for aphrodisiac treatment, one of which is a pack plant (Smilax
rotundifolia) which is commonly used to enlarge male genitalia in Papua Indonesia. Because these claims
are not scientifically tested and proven, at this time This study aims to determine the effect of the ethanol
extract of S. rotundifolia stem and leaf tubers on the parameters of sexual behavior in male Sprague Dawley
rats. As well as fear the most effective plant parts have aphrodisiac activity. Thirty rats were divided into
5 groups (A-E) consisting of group A given 0.5% Na CMC colloid solution (normal control), group B given
X-gra® suspension dosage 51.37 mg/kgBW (positive control), group C was given root ethanol extract
dosage 200 mg/kgBW, group D was given stem ethanol extract dosage 200 mg/kgBW and group E was
given leaf ethanol extract dosage 200 mg/kgBW. The aphrodisiac test was observed on the 31st day with
a ratio of male and female rats (1: 2). All parameters tested in the extract group showed significant
differences with the normal group. This showed an aphrodisiac effect in all extract groups. The 200
mg/kgBW stem extract group reduced latent rates and intromission mounts as well as increased
copulation rates, showing a marked increase in the number of intromissions, reduced ejaculatory latency

and inter-intromission interval, and increased ejaculation frequency. which was not significant in the X-
gra group (positive control) (p
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